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Drug Metabolism Prediction, Volume 63

by Johannes Kirchmair, Raimund Mannhold & Hugo Kubinyi

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists.

The authors provide more than a systematic overview of computational tools and knowledge...


The Role of the Study Director in Nonclinical Studies: Pharmaceuticals, Chemicals, Medical Devices, and Pesticides

by William J. Brock, Barbara Mounho & Lijie Fu

A single-source reference with a broad and holistic overview of nonclinical studies, this book offers critical training material and describes regulations of nonclinical testing through guidelines, models, case...


Profiles of Drug Substances, Excipients and Related Methodology

by Harry G. Brittain

Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug...


Handbook of Pharmacogenomics and Stratified Medicine

by Sandosh Padmanabhan

Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right...


Reputation and Power: Organizational Image and Pharmaceutical Regulation at the FDA: Organizational Image and Pharmaceutical Regulation at the FDA

by Daniel Carpenter

The U.S. Food and Drug Administration is the most powerful regulatory agency in the world. How did the FDA become so influential? And how exactly does it wield its extraordinary power? Reputation and Power traces...


Collaborative Innovation in Drug Discovery: Strategies for Public and Private Partnerships

by Rathnam Chaguturu & Ferid Murad

Can academia save the pharmaceutical industry?

The pharmaceutical industry is at a crossroads. The urgent need for novel therapies cannot stem the skyrocketing costs and plummeting productivity plaguing R&D,...


A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery

by Terry Kenakin

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, 4th Edition features the latest ideas and research about the application of pharmacology to the process of drug discovery to...


Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery

by Nicholas J. Brandon & Anthony R. West

This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these,...


Side Effects of Drugs Annual: A worldwide yearly survey of new data in adverse drug reactions

by Jeffrey K Aronson

The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then as a yearly update to the voluminous encyclopedia, Meyler's Side Effects of Drugs. Each new Annual continues...


Predictive Admet: Integrated Approaches in Drug Discovery and Development

by Jianling Wang & Laszlo Urban

This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so...


Drugs of Abuse: Pharmacology and Molecular Mechanisms

by Sherrel Howard

Drug abuse has been, and continues to be, a global societal issue with diverse sets of impacts. Drugs of Abuse: Pharmacology and Molecular Mechanisms introduces the basic principles of pharmacology and neuroscience...


Biophysical Methods for Biotherapeutics: Discovery and Development Applications

by Tapan K. Das

With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical development.

• Helps formulation and analytical scientists in pharma...


Phosphodiesterases and Their Inhibitors, Volume 61

by Spiros Liras, Andrew S. Bell & Raimund Mannhold

Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug.

Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets...


Emerging Targets & Therapeutics in the Treatment of Psychostimulant Abuse

by Linda P. Dwoskin

This new volume of Advances in Pharmacology presents the emerging targets and therapeutics in the treatment of psychostimulant abuse. With a variety of chapters and the best authors in the field, the volume...


Drug Stability for Pharmaceutical Scientists

by Thorsteinn Loftsson

Drug Stability for Pharmaceutical Scientists is a clear and easy-to-follow guide on drug degradation in pharmaceutical formulation. This book features valuable content on both aqueous and solid drug solutions,...


Toxicogenomics-Based Cellular Models: Alternatives to Animal Testing for Safety Assessment

by Jos Kleinjans

Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This...


Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases

by Christophe Wiart

Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases is the second volume in the series, Pharmaceutical Leads from Medicinal Plants. This book includes key pharmacological and...


International Cooperation, Convergence and Harmonization of Pharmaceutical Regulations: A Global Perspective

by Pierre-Louis Lezotre

International Cooperation, Convergence and Harmonization of Pharmaceutical Regulations: A Global Perspective provides the current status of the complex and broad phenomenon of cooperation, convergence and harmonization...


Natural Products in Medicinal Chemistry, Volume 60

by Stephen Hanessian, Hugo Kubinyi & Gerd Folkers

The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters.

Using...


Ocular Transporters and Receptors: Their Role in Drug Delivery

by A K Mitra

Ocular transporters and receptors contains detailed descriptions of major transporters and receptors expressed in the eye, with special emphasis on their role in drug delivery. The complex anatomy and the existence...