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Pharmacology & Therapeutics of Constitutively Active Receptors

by Ya-Xiong Tao

Volume 70 of Advances in Pharmacology presents the pharmacology and therapeutics of constitutively active receptors. With a variety of chapters and the best authors in the field, the volume is an essential resource...


Psychopharmacology Problem Solving: Principles and Practices to Get It Right

by F. Scott Kraly

At last, a clinician’s guidebook to prescription dilemmas. Psychotropic medications prescribed to treat mental disorders have become increasingly commonplace over the past half century, but the decision-making...


Drug Metabolism Prediction, Volume 63

by Johannes Kirchmair, Raimund Mannhold & Hugo Kubinyi

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists.

The authors provide more than a systematic overview of computational tools and knowledge...


The Role of the Study Director in Nonclinical Studies: Pharmaceuticals, Chemicals, Medical Devices, and Pesticides

by William J. Brock, Barbara Mounho & Lijie Fu

A single-source reference with a broad and holistic overview of nonclinical studies, this book offers critical training material and describes regulations of nonclinical testing through guidelines, models, case...


Applied Physical Pharmacy 2/E

by Mansoor Amiji & Thomas J. Cook

A UNIQUE PRACTICE-ORIENTED INTRODUCTION TO PHYSICAL PHARMACY

Applied Physical Pharmacy explores the fundamental physicochemical properties and processes important for understanding how drugs are transformed...


Profiles of Drug Substances, Excipients and Related Methodology

by Harry G. Brittain

Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug...


Handbook of Pharmacogenomics and Stratified Medicine

by Sandosh Padmanabhan

Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right...


Reputation and Power: Organizational Image and Pharmaceutical Regulation at the FDA

by Daniel Carpenter

The U.S. Food and Drug Administration is the most powerful regulatory agency in the world. How did the FDA become so influential? And how exactly does it wield its extraordinary power? Reputation and Power traces...


Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery

by Nicholas J. Brandon & Anthony R. West

This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these,...


Side Effects of Drugs Annual: A worldwide yearly survey of new data in adverse drug reactions

by Jeffrey K Aronson

The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then as a yearly update to the voluminous encyclopedia, Meyler's Side Effects of Drugs. Each new Annual continues...


Predictive Admet: Integrated Approaches in Drug Discovery and Development

by Jianling Wang & Laszlo Urban

This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so...


Lost in Translation: Barriers to Incentives for Translational Research in Medical Sciences

by Rakesh Srivastava, Wojciech Maksymowicz & Wlodek Lopaczynski

This book is all about the definition and finding ways to prioritize and accelerate translation research in biomedical sciences and rapidly turning new knowledge into first-in-human studies. It represents an...


Phosphodiesterases and Their Inhibitors, Volume 61

by Spiros Liras, Andrew S. Bell & Raimund Mannhold

Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug.

Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets...


Emerging Targets & Therapeutics in the Treatment of Psychostimulant Abuse

by Linda P. Dwoskin

This new volume of Advances in Pharmacology presents the emerging targets and therapeutics in the treatment of psychostimulant abuse. With a variety of chapters and the best authors in the field, the volume...


Pharmacotherapy A Pathophysiologic Approach 9/E

by Joseph DiPiro, Robert L. Talbert & Gary Yee

25 ADDITIONAL CHAPTERS AVAILABLE ONLINE

THE LANDMARK TEXT ON HOW TO ACHIEVE OPTIMAL PATIENT OUTCOMES THROUGH EVIDENCE-BASED MEDICATION THERAPY

Pharmacotherapy: A Pathophysiologic Approach is written to help...


Advanced Textbook on Gene Transfer, Gene Therapy and Genetic Pharmacology: Principles, Delivery and Pharmacological and Biomedical Applications of Nuc

by Daniel Scherman

This unique advanced textbook provides a clear and comprehensive description of the field of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set...


Natural Products in Medicinal Chemistry, Volume 60

by Stephen Hanessian, Hugo Kubinyi & Gerd Folkers

The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters.

Using...


Multiple Sclerosis. A Guide to Pharmacologic Treatment

by Daniel Ontaneda

The arena of multiple sclerosis (MS) treatment has changed substantially over the past 20 years. Now nine different agents are approved for use in MS with several different routes of administration, safety characteristics...


Drug Delivery Applications of Noninvasive Imaging: Validation from Biodistribution to Sites of Action

by Chun Li & Mei Tian

Cost-effective strategies for designing novel drug delivery systems that target a broad range of disease conditions

In vivo imaging has become an important tool for the development of new drug delivery systems,...


Scaffold Hopping in Medicinal Chemistry, Volume 58

by Nathan Brown, Raimund Mannhold & Hugo Kubinyi

This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects.

The first section serves as an introduction...