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General and Molecular Pharmacology: Principles of Drug Action

by Francesco Clementi & Guido Fumagalli

With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention  to the mechanisms...


Nonclinical Assessment of Abuse Potential for New Pharmaceuticals

by Carrie Markgraf, Thomas Hudzik & David Compton

Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal...


Patient Reported Outcomes

by Annabel Nixon, Diane Wild & Willie Muehlhausen

Patient reported outcomes (PROs) are a measurement based on a report that comes directly from the patient about the status of their health condition without amendment or interpretation of the patient’s response...


Profiles of Drug Substances, Excipients, and Related Methodology

by Harry G. Brittain

Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug...


Radiochemical Syntheses, Volume 2

by Peter J. H. Scott & Michael R. Kilbourn

This book describes methods and procedures for preparing PET radiopharmaceuticals, and highlights new methods for conducting radiochemical reactions with carbon-11 (C11) and fluorine-18 (F18), which are two...


Radiochemical Syntheses, Volume 2: Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production

by Peter J. H. Scott & Michael R. Kilbourn

This book describes methods and procedures for preparing PET radiopharmaceuticals, and highlights new methods for conducting radiochemical reactions with carbon-11 (C11) and fluorine-18 (F18), which are two...


The Thirteenth Step: Addiction in the Age of Brain Science

by Markus Heilig

The past twenty-five years have witnessed a revolution in the science of addiction, yet we still rely upon sorely outdated methods of treatment. Expensive new programs for managing addiction are also flourishing,...


Phytotherapies: Efficacy, Safety, and Regulation

by Iqbal Ramzan

Covering fundamentals and new developments in phytotherapy, this book combines pharmaceutical sciences and chemistry with clinical issues.

•    Helps readers better understand phytotherapy and learn the...


The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

by Joerg Bluemel, Sven Korte & Emanuel Schenck

The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity...


Cardiovascular Diseases: From Molecular Pharmacology to Evidence-Based Therapeutics

by Y. Robert Li

Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management...


Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment

by Kunal Roy, Supratik Kar & Rudra Narayan Das

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment describes the historical evolution of quantitative structure-activity relationship (QSAR) approaches and their...


Peptide Chemistry and Drug Design

by Ben M. Dunn

This book focuses on peptides as drugs, a growing area of pharmaceutical research and development. It helps readers solve problems of discovering, developing, producing, and delivering peptide-based drugs.

• Identifies...


Progress in Medicinal Chemistry

by G. Lawton & David R. Witty

Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics,  fluorine in medicinal chemistry,...


Thermodynamics and Kinetics of Drug Binding, Volume 65

by György Keserü & David Swinney

This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects.

Divided...


Antitargets and Drug Safety

by Laszlo Urban, Vinod Patel & Roy J. Vaz

With its focus on emerging concerns of kinase and GPCR-mediated antitarget effects, this vital reference for drug developers addresses one of the hot topics in drug safety now and in future.

Divided into three...


Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part A

by Uwe Rudolph

This new volume of Advances in Pharmacology presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years which has revealed specific physiological and pharmacological...


Blood-Brain Barrier in Drug Discovery: Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs

by Li Di & Edward H. Kerns

Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant...


Successful Drug Discovery

by Janos Fischer

The first volume of the book series "Successful Drug Discovery" is focusing on new drug discoveries during the last decade, from established drugs to recently introduced drugs of all kinds: small-molecule-,...


Personalized Cancer Chemotherapy: An Effective Way of Enhancing Outcomes in Clinics

by Da Yong Lu

Personalized Cancer Chemotherapy separately describes and addresses "individualized cancer chemotherapy" (ICC) strategies new and old, to provide readers with new insights into their characteristics and techniques,...


Basic and Clinical Pharmacology 13 E

by Bertram Katzung & Anthony Trevor

Gain a full understanding of the basic science and clinical use of drugs with the most up-to-date and comprehensive pharmacology text in the health sciences

400 ILLUSTRATIONS--MANY IN FULL COLOR

Organized to...