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Natural Products in Medicinal Chemistry

by Stephen Hanessian, Hugo Kubinyi & Gerd Folkers

The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters.

Using...


Cancer Drug Design and Discovery

by Stephen Neidle

Cancer Drug Design and Discovery, 2nd edition is an important reference on the underlying principles for the design and subsequent development of new anticancer small molecule agents. New chapters have been...


Scaffold Hopping in Medicinal Chemistry, Volume 58

by Nathan Brown, Raimund Mannhold & Hugo Kubinyi

This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects.

The first section serves as an introduction...


Multiple Sclerosis. A Guide to Pharmacologic Treatment

by Daniel Ontaneda

The arena of multiple sclerosis (MS) treatment has changed substantially over the past 20 years. Now nine different agents are approved for use in MS with several different routes of administration, safety characteristics...


Drug Delivery Applications of Noninvasive Imaging: Validation from Biodistribution to Sites of Action

by Chun Li & Mei Tian

Cost-effective strategies for designing novel drug delivery systems that target a broad range of disease conditions

In vivo imaging has become an important tool for the development of new drug delivery systems,...


Data Mining in Drug Discovery, Volume 57

by Ré Hoffmann, Arnaud Gohier & Pavel Pospisil

Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening...


The Leukemia-Lymphoma Cell Line Factsbook

by Hans G. Drexler

This book represents an essential reference manual for all of the well-characterized leukemia-lymphoma cell lines currently available. It provides the most important facts, using the succinct and user-friendly...


Social Learning In Animals: The Roots of Culture

by Cecilia M. Heyes & Jr., Bennett G. Galef

The increasing realization among behaviorists and psychologists is that many animals learn by observation as members of social systems. Such settings contribute to the formation of culture. This book combines...


Translational Medicine - What, Why and How: An International Perspective

by B. Alving, K. Dai & S.H.H. Chan

This book is the first to provide an aerial view, as well as detailed information, on 'how' activities in translational medicine are under development in countries such as the USA, China, the UK, and Taiwan....


Cell/Tissue Injury and Cytoprotection/Organoprotection in the Gastrointestinal Tract

by L.P. Filaretova & K. Takeuchi

In recent years, there have been significant advances both in understanding the mechanisms involved in gastrointestinal mucosal injury and protection, as well as in the development of successful strategies for...


Inflammation in Psychiatry

by A. Halaris & B.E. Leonard

Psychoimmunology is a rapidly maturing area of scientific endeavor that provides a compelling integrative link between the immune system and its response to stress and psychiatric illness. Stress initiates pathological...


Antibiotics: Targets, Mechanisms and Resistance

by Claudio O. Gualerzi, Letizia Brandi & Attilio Fabbretti

Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics,...


Pharmacotherapy Principles and Practice Study Guide 3/E

by Michael Katz & Kathryn R. Matthias

More than 100 cases teach how you how to apply pharmacotherapeutic concepts to real-world clinical situations

Pharmacotherapy Principles and Practice Study Guide, Third Edition, includes more than 100 patient...


In Vitro Methods in Pharmaceutical Research

by Jose V. Castell & Maria Jose Gmez-Lechn

In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform...


Advanced Drug Delivery

by Ashim Mitra, Chi H. Lee & Kun Cheng

Provides both fundamentals and new and emerging applications

Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic...


Biological Drug Products: Development and Strategies

by Wei Wang & Manmohan Singh

Tested and proven solutions to the challenges of biological drug product development

Biological drug products play a central role in combating human diseases; however, developing new successful biological drugs...


Case Files Pharmacology, Third Edition

by Eugene Toy & David Loose

REAL-LIFE CLINICAL CASES FOR THE BASIC SCIENCES AND USMLE STEP 1

Experience with clinical cases is key to excelling on the USMLE Step 1 and shelf exams, and ultimately to providing patients with competent clinical...


Hormones

by Anthony W. Norman & Gerald Litwack

The newly revised and updated Hormones, Second Edition provides a comprehensive treatment of human hormones, viewed in light of modern theories of hormone action and in the context of current understanding of...


Medical Applications of Liposomes

by D.D. Lasic & D. Papahadjopoulos

The development of liposomes as a drug delivery system has fluctuated since its introduction in the late 1960's by A.D. Bangham. While academic research of liposomes as a model membrane system has always flourished,...


Brain Mapping: The Disorders: The Disorders

by John C. Mazziotta, Arthur W. Toga & Richard S.J. Frackowiak

Brain Mapping: The Disorders is the first comprehensive text to describe the uses of the latest brain mapping technologies in the evaluation of patients with neurological, neurosurgical and psychiatric disorders....