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Lost in Translation: Barriers to Incentives for Translational Research in Medical Sciences

by Rakesh Srivastava, Wojciech Maksymowicz & Wlodek Lopaczynski

This book is all about the definition and finding ways to prioritize and accelerate translation research in biomedical sciences and rapidly turning new knowledge into first-in-human studies. It represents an...


Handbook of the Behavioral Neurobiology of Serotonin

by Christian P. Muller & Barry Jacobs

Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially...


Drug Transporters: Molecular Characterization and Role in Drug Disposition

by Guofeng You, Marilyn E. Morris & Binghe Wang

This new edition overviews drug transporters and presents the principles of drug transport and associated techniques, featuring new chapters on multidrug and toxin extrusion proteins, placental transport, ...


Pharmacology & Therapeutics of Constitutively Active Receptors

by Ya-Xiong Tao

Volume 70 of Advances in Pharmacology presents the pharmacology and therapeutics of constitutively active receptors. With a variety of chapters and the best authors in the field, the volume is an essential resource...


Drug Metabolism Prediction

by Johannes Kirchmair, Raimund Mannhold & Hugo Kubinyi

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists.

The authors provide more than a systematic overview of computational tools and knowledge...


Toxicological Survey of African Medicinal Plants

by Victor Kuete

Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and...


Shadow Medicine: The Placebo in Conventional and Alternative Therapies

by John S. Haller

A distinguished historian of medicine, John S. Haller Jr. explores the epistemological foundations of evidence-based medicine (EBM) and the challenges it presents for both conventional and alternative therapies....


Debates in History Teaching

by Ian Davies

Debates in History Teaching encourages teachers to engage with and reflect on key issues, concepts and debates in their subject. It supports you in reaching your own informed judgements, enabling you to discuss...


Handbook of Pharmacogenomics and Stratified Medicine

by Sandosh Padmanabhan

Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right...


Handbook of Clinical Psychopharmacology for Therapists

by John D. Preston, John H. O'Neal & Mary C. Talaga

This seventh edition of The Handbook of Clinical Psychopharmacology for Therapists includes the latest updates on medications for mental health disorders and their side effects along with a new chapter on the...


Profiles of Drug Substances, Excipients and Related Methodology

by Harry G. Brittain

Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug...


The Role of the Study Director in Nonclinical Studies: Pharmaceuticals, Chemicals, Medical Devices, and Pesticides

by William J. Brock, Barbara Mounho & Lijie Fu

A single-source reference with a broad and holistic overview of nonclinical studies, this book offers critical training material and describes regulations of nonclinical testing through guidelines, models, case...


Psychopharmacology Problem Solving: Principles and Practices to Get It Right

by F. Scott Kraly

At last, a clinician’s guidebook to prescription dilemmas. Psychotropic medications prescribed to treat mental disorders have become increasingly commonplace over the past half century, but the decision-making...


Advanced Textbook on Gene Transfer, Gene Therapy and Genetic Pharmacology: Principles, Delivery and Pharmacological and Biomedical Applications of Nuc

by Daniel Scherman

This unique advanced textbook provides a clear and comprehensive description of the field of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set...


Autoimmune Disease Models

by Irun R. Cohen & Ariel Miller

Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune...


Pharmaceutical Toxicology in Practice: A Guide to Non-Clinical Development

by Alberto Lodola & Jeanne Stadler

This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an understanding...


Reputation and Power: Organizational Image and Pharmaceutical Regulation at the FDA

by Daniel Carpenter

The U.S. Food and Drug Administration is the most powerful regulatory agency in the world. How did the FDA become so influential? And how exactly does it wield its extraordinary power? Reputation and Power traces...


CLINICAL PSYCHOPHARMACOLOGY: A PRACTICAL APPROACH: A Practical Approach

by Humberto Marin & Javier I Escobar

This book aims to provide comprehensive, up-to-date information on psychotropic drugs and inform clinical decisions for the treatment of mental disorders using a problem-solving approach.

In order to accomplish...


Phosphodiesterases and Their Inhibitors

by Spiros Liras, Andrew S. Bell & Raimund Mannhold

Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug.

Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets...


Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery

by Nicholas J. Brandon & Anthony R. West

This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these,...