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This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defence pathway, Animal models of drug-induced idiosyncratic...
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected...
Most of the 75 million Americans who have high blood pressure need medication to control it, but many are prescribed medication that is wrong for them. Dr. Mann reveals how readers, with the oversight of their...
This two-volume set provides an in-depth look at one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. The inclusion of the latest information on diagnostic...
With the improvements in formulation science and certain transdermal delivery technologies, the non-invasive mode of drug delivery is now ready to compete with traditional methods of oral and injectible routes...
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism.
As such, it provides a ready reference on the principles and methods...
This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes...
This is the eBook version of the printed book.
Today, many manufacturers of plant-based "neuroceuticals" claim their products can offer powerful benefits in brain function. However, the US government does not...
Elsevier now offers a series of derivative works based on the acclaimed Meyler's Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing biomedical researcher...
Elsevier now offers a series of derivative works based on the acclaimed Meyler's Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing physician and/or...
This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than 40 years, The Alkaloids: Chemistry and Biology, founded by the late Professor...
In The Fungal Pharmacy, noted herbalist Robert Rogers introduces readers to more than 300 species of medicinal mushrooms and lichens found in North America. These fungi, Rogers explains, have the capacity to...
New and emerging directions in pharmaceutical research to better treat schizophrenia
Although the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches...
The opportunities and challenges of using dendrimers to improve drug delivery
Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest....
Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development.
The first part provides a basic understanding of the...
The how's and why's of successful drug repositioning
Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines...
Elsevier now offers a series of derivative works based on the acclaimed Meyler's Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing biomedical researcher...
Cost-effective manufacturing of biopharmaceutical products is rapidly gaining in importance, while healthcare systems across the globe are looking to contain costs and improve efficiency. To adapt to these changes,...
American doctors dispense approximately 230 million antidepressant prescriptions every year, more than any other class of medication. Charles Barber explores this disturbing phenomenon, examining the ways in...
A comprehensive guide to optimizing the lifecycle management of pharmaceutical brands
The mounting challenges posed by cost containment policies and the prevalence of generic alternatives make optimizing the...