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A comprehensive look at current drug discovery and development methods—and the roadmap for the future
Providing both understanding and guidance in characterizing potential drugs and their production and synthesis,...
Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the "bench to bedside" translational approach to drug development.
Clearly structured into...
In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid...
Development of Vaccines: From Discovery to Clinical Testing outlines the critical steps, and analytical tools and techniques, needed to take a vaccine from discovery through a successful clinical trial. Contributions...
This book, which is the translated version of a Swedish book, combines a general introduction of a variety of antibiotics with a more in-depth discussion of resistance. The focus on resistance in learning about...
Pediatric Drug Development: Concepts and Applications is designed as a reference and textbook and is meant to address the science of differences between the pediatric and adult subject in the development of...
Discover how biomarkers can boost the success rate of drug development efforts
As pharmaceutical companies struggle to improve the success rate and cost-effectiveness of the drug development process, biomarkers...
A comprehensive resource on case studies of marketed kinase drugs and promising drug trials
Since the discovery of protein kinase activity in 1954, the field of protein kinase drug discovery has advanced dramatically....
An expert guide to targeting protein kinases in cancer therapy
Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because...
Traditional column chromatography dominates current purification technology, and many of the productivity gains that have been achieved have relied on upscaling such devices. However, this comes with a cost...
"Concise and easy to read, the book quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs."
—Doody's Reviews, May...
The first book to focus on comprehensive systems biology as applied to drug discovery and development
Drawing on real-life examples, Systems Biology in Drug Discovery and Development presents practical applications...
The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery
An instrumental analytical method for quantifying the mass and characterization of various...
This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The...
Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional structures of both...
Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology
Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and...
Understand and assess the design, delivery, and efficacy of orally administered drugs
A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral...
This book overviews and integrates the business and technical issues that pharmaceutical companies need to know in order to combat the major global problem of counterfeit medicines. In addition to discussion...
Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological agents
Drug discrimination can be described as a "drug detection"...
The book addresses the basics, applications, and manufacturing of plasmid biopharmaceuticals. The survey of the most relevant characteristics of plasmids provides the basics for designing plasmid products (applications)...
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