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A Look Back

by Scientific American Editors

It’s hard to believe 2012 is coming to a close. Lucky for us, this year has seen some amazing science, and in this eBook, we’ve compiled Scientific American’s best stories of 2012 with an eye on content,...


Bridging Divides: The Origins of the Beckman Institute at Illinois

by Theodore L. Brown

Bridging Divides offers a first-hand account of the origins of the Beckman Institute for Advanced Science and Technology, an interdisciplinary research institute at the University of Illinois at Urbana-Champaign...


Sex Determination and Sexual Development

by Mark Van Doren

This volume reviews our current understanding for how sex determination is initiated and how it results in sexual dimorphic development. Chapters discussing work on different model systems provide a basis for...


The Ovary

by Peter C.K. Leung & Eli Y. Adashi

This second edition of The Ovary incorporates the dramatic research developments regarding the ovarian life cycle within the past decade.

It looks at ovarian function from a detailed molecular and cellular level....


Complex enzymes in microbial natural product biosynthesis, Part B: polyketides, aminocoumarins and carbohydrates: polyketides, aminocoumarins and carb

by David A. Hopwood

Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer...


Mouse Models of Developmental Genetic Disease

by Robert Krauss

Approximately three percent of newborn humans have congenital anomalies with significant cosmetic and/or functional consequences. Much of our ability to understand what has gone awry in these birth defects rests...


AID for Immunoglobulin Diversity: Advances in Immunology

by Frederick W. Alt

Advances in Immunology, a long established and highly respected serial, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology,...


Molecular Biology of B Cells

by Tasuku Honjo & Frederick W. Alt

Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described...


Lipidomics and Bioactive Lipids:  Mass Spectrometry Based Lipid Analysis: Mass Spectrometry Based Lipid Analysis

by H. Alex Brown

This volume in the well-established Methods in Enzymology series features methods for the study of lipids using mass spectrometry techniques. Articles in this volume cover topics such as Qualitative Analysis...


Oxidative Stress and Neurodegenerative Disorders

by G. Ali Qureshi & S. Hasan Parvez

Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species...


Methods in Nano Cell Biology

by Bhanu Ramaswamy

Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Nanobiology focuses on the properties and structure of complex assemblies...


Essential Statistical Methods for Medical Statistics

by Philip Miller

Essential Statistical Methods for Medical Statistics presents only key contributions which have been selected from the volume in the Handbook of Statistics: Medical Statistics, Volume 27 (2009).

While the use...


Long-Range Control of Gene Expression

by Veronica van Heyningen & Robert E Hill

This volume covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin...


Stem Cell Culture: Methods in Cell Biology

by Jennie P. Mather

The purpose of this volume is to provide a comprehensive resource for researchers in the fields of embyonic, fetal and adult stem cell biology to find methods for the purification, culture, and differentitation...


Fluorescence Spectroscopy

by Ludwig Brand & Michael L. Johnson

Fluorescence spectroscopy is a type of electromagnetic spectroscopy, using a beam of light, which analyzes fluorescence from a sample. Given its extremely high sensitivity and selectivity, it is an important...


Numerical Computer Methods, Part D

by Ludwig Brand & Michael L. Johnson

The aim of this volume is to brief researchers of the importance of data analysis in enzymology, and of the modern methods that have developed concomitantly with computer hardware. It is also to validate researchers'...


Bioengineering and Molecular Biology of Plant Pathways

by Norman Lewis, Hans J. Bohnert & Henry Nguyen

The increased knowledge about the structure of genomes in a number of species, about the complexity of transcriptomes, and the rapid growth in knowledge about mutant phenotypes have set off the large scale use...


Movement Disorders: Genetics and Models

by Mark S. LeDoux

The use of animal models is a key aspect of scientific research in numerous fields of medicine. This book vigorously examines the important contributions and application of animal models to the understanding...


Nature's Music: The Science of Birdsong

by Peter R. Marler & Hans Slabbekoorn

The voices of birds have always been a source of fascination. Nature's Music brings together some of the world's experts on birdsong, to review the advances that have taken place in our understanding of how...


International Review of Cell and Molecular Biology

by Kwang W. Jeon

International Review of Cell & Molecular Biology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic...